2012년 8월 10일 금요일

insufficient lactation, hypogalactia

Multicentral randomized controlled studies on acupuncture at Shaoze (SI 1) for treatment of postpartum hypolactation, 2007

Wang HC, An JM, Han Y, Huang LN, Zhao JW, Wei LX, Dong L, Zhai GR, Li XP, Yang AJ, Gu M.
Zhongguo Zhen Jiu.

Abstract
OBJECTIVE:
To explore effect of acupuncture at Shaoze (SI 1) for treatment of postpartum hypolactation.

METHODS:
Multicentral randomized controlled and single blind clinical trial was adopted, and 276 cases were divided into a treatment group and a control group, 138 cases in each group. The treatment group were treated with electroacupuncture (EA) at Shaoze (SI 1) and the control group with EA at Shangyang (LI 1). After treatment of 2 courses, the therapeutic effects and changes of cumulative score of TCM symptoms, mammary filling degree, lactation amount, prolactin level were evaluated and investigated.

RESULTS:
The cured and markedly effective rate was 97.8% in the treatment group and 24.3% in the control group with a significant difference between the two groups (P < 0.05). The treatment group in improvement of the cumulative score of TCM symptoms and the mammary filling degree, and increasing the lactation amount and the prolactin level were better than the control group (P < 0.01).

CONCLUSION:
Acupuncture at Shaoze (SI 1) has obvious therapeutic effect on hypolactation.

-> 원문 못 찾음.



Clinical Observation on the Treatment of Post-cesarean Hypogalactia by Auricular Points Sticking-Pressing, 2009

ZHOU Hai-yan (周海燕), LI Li (李 力), LI Dan (李 丹), LI Xia (李 霞), MENG Hong-juan (孟红娟), GAO Xue-mei (高雪梅), JIANG Hui-jun (姜慧君), CAO Li-rong (曹丽蓉), and ZHU Yi-ling (朱一麟)
Chin J Integr Med


ABSTRACT
Objective: To explore the effect of auricular points sticking-pressing (APSP) in treating postcesarean hypogalactia (PCH).

Methods: A randomized, controlled, single-blinded clinical trial on 116 patients with PCH was carried out. They were equally assigned to the treatment group and the control group. The treatment group received APSP, with the pellets pressed for 4 times daily, while the control group was only asked to do lactation to meet infant demand. The therapeutic effifi cacy and the changes in scores of traditional Chinese medicine (TCM) syndrome, volume of milk secretion, supplementary feeding and serum level of prolactin (PRL) in the two groups were estimated and compared after the patients had been treated for 5 days.

Results: The cured and markedly effective rate in the treatment group was 89.7%, which was signififi cantly higher than that in the control group (27.6%, <0 .05=".05" 0.2527="0.2527" 95="95" and="and" ci="ci" decrease="decrease" elevation="elevation" feeding="feeding" improvement="improvement" in="in" increase="increase" level="level" milking="milking" of="of" p="p" prl="prl" revealed="revealed" supplementary="supplementary" syndrome="syndrome" tcm="tcm" the="the" volume="volume">the treatment group were all superior to those in the control group, showing statistical signififi cance ( <0 .01=".01" p="p">
Conclusion: APSP shows an apparent effifi cacy in treating PCH and is worthy of application in clinical practice.

변증기준
(1) Qi-blood deficiency type(QBD):
little or even none of milk secretion,
thin milk,
soft mammary gland with no distending sensation,
lusterless complexion,
listlessness,
poor appetite,
pale tongue with thin-white coating,
fine-weak pulse;
(2) Gan (肝)-qi stagnancy type (GQS):
little or even none of milk secretion,
slimy milk,
distention and painful mammary gland,
dysthymia,
distending pain in the chest and hypochondriac region,
poor appetite,
dark-red tongue or with reddened tip and margin, thin-yellow coating,
wiry thready or wiry quick pulse

The severity of hypogalactia
(1) mild: volume of milk secreted met 2/3 of infants' requirement;
(2) moderate: up to 1/3;
(3) severe: almost no milk secretion, unable to lactate

주이혈점
유방점, 내분비점
  기혈부족시 비점, 위점
간기울결시 간점, 신문점

Vaccaria seeds were stuck and fi xed on the sensitive auricular points detected by a metal probe with zinc paste in 0.6 cm× 0.6 cm, with each pressed
individually for 1 min to induce stimulus until patients felt endurable heat and distending pain on auricles, and the pressing repeated for 4 times every day.
The pressing was performed once a day, beginning from the first day after cesarean, for 5 days in total. Meanwhile, the patients were encouraged to do breast feeding for no less than 8 times every day.






-> 이침이 PRL 수치를 증가시켜 모유량을 증가시킨다고 봄.

Galactorrhoea Following Acupuncture, 2012

Chris Jenner, Jacqueline Filshie.


일측 유방절제술을 받은 41세 여성에서 통증 치료 목적으로 받은 침 치료 중 건측에서 galactorrhea 발생함.

She was given paravertebral acupuncture at C7, T1, T2 and T4, which included the intercostobrachial nerve distribution, and trigger points in infraspinatus and the  suprascapular region were needled. The lymphoedematous right arm was avoided. Points on the left arm were treated; these included the traditional acupuncture point LI4.

호르몬 검사는 하지 않음.


Study on clinical efficacy of needling Danzhong(CV 17) in treating postpartum hypogalactia. 2008

JOURNAL OF ACUPUNCTURE AND TUINA SCIENCE
Tao Huang, Bao-ying Chen, Jun-qin He, Jian Bai, Mei Gu, Hong-tao Cao, Mei-jie He, Xin Li, Jing-wei Jiang and Gui-rong Zhai, et al.


Abstract

Objective  
To investigate the clinical efficacy of needling Danzhong(CV 17) in the treatment of postpartum hypogalactia and provide clinical evidence for indications of the point.

Methods  
A multi-centre single-blind randomized controlled trial was carried out. (276명)Two hundred and seventy-six puerperal women with postpartum hypogalactia were randomly allocated into acupuncture group and herb group, and respectively treated for three consecutive days(3일 동안 치료). The degree of mammary fullness, the amount of milk secreted, prolactin, baby weight, the frequency and volume of artificial feeding, the number of infant urination events, and the duration of baby crying were observed. The clinical curative effects on postpartum hypogalactia were compared.

Results  
Hypogalactia was effectively treated in both acupuncture and herb groups. There were statistically significant differences in degree of mammary fullness, amount of milk secreted, baby weight, the frequency and amount of artificial feeding, and the number of infant urination events between pretreatment and post-treatment, but no difference between the two groups. There was no significant difference in prolactin in the acupuncture group and there was a difference in prolactin in the herb group between pretreatment and posttreatment.

Conclusion  
Needling Danzhong(CV 17) can effectively promote lactation.



Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in), a Traditional Herbal Medicine, Stimulates Lactation with Increase in Secretion of Prolactin but not Oxytocin in the Postpartum Period, 2007

The American Journal of Chinese Medicine
Takahisa Ushiroyama


Abstract: The aim of the present investigation was to evaluate the clinical efficacy of Xionggui-tiao-xue-yin, a traditional Japanese herbal medicine, in stimulating lactation in the postpartum period. We enrolled 82 women who had a normal delivery in Osaka Medical College Hospital, and randomly assigned them to the following two groups: a group of 41 women who received Xiong-gui-tiao-xue-yin at a dose of 6.0 g/day (Group X), and a group of 41 women who received ergometrine (methylergometrine maleate) at a dose of 0.375 mg/day (Group E). Volume of lactation was determined daily until Day 6 postpartum. Plasma prolactin and oxytocin concentration were measured at Days 1 and 6 postpartum. The results showed that volume of lactation was significantly higher in Group X than in Group E at Days 4 (p = 0.042), 5 (p = 0.038), and 6 (p = 0.046). Significant differences between Groups X and E were noted in plasma prolactin concentration at Days 1 (157.9 ±  78.2 ng/ml and 129.1 ± 64.8 ng/ml; p = 0.037) and 6 (167.5 ± 95.4 ng/ml and 117.1 ± 53.6 ng/ml; p = 0.0042) postpartum. On the other hand, at Day 1, oxytocin concentration was significantly higher in Group E than in Group X (p = 0.0024). No adverse effects were observed in this study. 
The results of our study demonstrate the beneficial effects of Xiong-gui-tiao-xue-yin on lactation, with increase in prolactin level without increase in oxytocin level in the postpartum period. Therefore, Xiong-gui-tiao-xue-yin can be expected to improve lactation in women in the postpartum period. Further detailed bio-pharmacological studies and clinical trials to investigate the properties of this drug are warranted.