2012년 7월 19일 목요일

Prevalence of hyperglycemia during pregnancyaccording to maternal age and pre-pregnancy body mass index in Japan, 2007–2009


Abstract

Objective

To assess the prevalence of hyperglycemiaaccording to maternal age and pre-pregnancy body mass index (BMI) among Japanese women before introduction of the current diagnostic criteria.

Methods

In a retrospective study, data were analyzed from women with singleton pregnancies who were registered with the JSOG Successive Pregnancy Birth Registry System and who gave birth at 22 weeks of gestation or more between January 2007 and December 2009.

Results

Among 138 530 women, 3667 (2.6%) were diagnosed with hyperglycemia including gestational diabetes and diabetes mellitus. The prevalence of hyperglycemia increased with advancing maternal age and increasing BMI. Among women aged ≤ 24, 25–34, 35–39, and ≥ 40 years, the prevalence was 0.4%, 0.8%, 1.5%, and 4.0%, respectively, in lean women (BMI < 18.5); 1.0%, 1.6%, 2.3%, and 3.1%, respectively, in normal weight women (BMI 18.5–24.9); and 5.7%, 9.2%, 12.9%, and 15.2%, respectively, in obese women (BMI ≥ 25.0). Of the 1181 newborns with a birth weight of 4000 g or more, 1046 (88.6%) were born to women not diagnosed with hyperglycemia.

Conclusion

The results may reflect the baseline prevalence of hyperglycemia and macrosomic neonates (birth weight ≥ 4000 g) during the era of the old diagnostic criteria in Japan.

GDM/DM 그룹에서 임신 전 BMI가 높은 군의 비율이 높음
고령과 GDM/DM 그룹은 상관관계가 있음.

35세 이상 BMI 25이상에서 높은 관측빈도가 나타남
특히, 나이 요인보다는 임신전 BMI가 더 많은 영향을 주는 것으로 보임.

고혈당에 대한 유병율
기준값보다 BMI 상대위험도는 5.65, 고령은 3.04, 고령 BMI는 최대 15.1까지 나타남.
 




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